NeuroClimax is a proprietary nasal nootropic formulation spray for brain regeneration enhancer with organic nootropic grade active ingredients. It supports memory, learning, cognitive enhancement, brain energy and focus through novel regenerative cognitive increase using brain plasticity mechanisms in neurons with compelling pre-clinical trial evidence to re-generate neurons in models of cognitive decline, and even at chemical lesion brain disease models (models of neurodegeneration).
How does it work? Two nootropic agents' classes are biologics derived from a plant (Cyclic AMP enhancers enantiomers + forskolin) and synthesized glutaminergic peptide agonists of memory receptors. In combination, the nootropic agents provide potent neurotrophic support by increasing the level of Cyclic AMP, Brain-Derived Neurotrophic Factor and Nerve Growth Factor. By increase the levels of Cyclic AMP, BDNF and NGF in the brain, these neurotrophic factors are known to increase brain energy by increasing the level of ATP, increase the formation of neuronal networks and circuits, and activate neuronal re-development and growth of new neurons by NGF.
Overall, this unique powerful brain targeting enhancing technology is only one known to enable brain repair mechanisms (kinases proteins of brain connectivity increase), and new neuronal formations that were lost during neurodegeneration (chemical lesions) and reinstate motor, energy, and intellectual brain capabilities with the end goal is to increase quality of life (Dagda & Dagda, 2022)
The key ingredients are safe and have been used in clinical studies. For instance, Cyclic amp enhancers have been used to treat anxiety, mood disorders and depression. Glutaminergic peptide agonists of memory receptors have been shown in two clinical studies to increase cognitive function, reduce fatigue, elevate mood, and reduce anxiety.
By combining both of the class of nootropics as a nootropic stack directly to the brain, these two active ingredients have been shown in preclinical studies to activate a positive loop in the brain that provides an additive effect in enhancing brain health, brain energy (Dagda & Dagda, 2022)
NeuroClimax brand products are manufactured and distributed by CNS Curative Technologies and is a registered trademark brand owned and managed by CNS Curative Technologies LLC under USPTO numbers: 98309088, 98309099 and 98309108.
https://www.cnscurative.com
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NeuroClimax brain innovation in models of Cognitive decline and chemical lesions of neurons
In the case of neurodegenerative disease models of cognitive decline, the low levels of neurotrophic factors are found to very low levels in brain (PKA, cyclic AMP, BDNF) but increases up to three-fold after administration of NeuroClimax for at least 10 days. For more information about the preclinical evidence of NeuroClimax Advanced, please see the list of publications published from our research team (The Science behind how this works) below.
Why order:
- Only made in Nevada
- USDA certified for quality, and safety
- Sterile formulation
- Unique high potency brain targeting antidepressive mechanism in brain
- Fast acting in less than 15 minutes
-Long lasting more than 8 hours
Safety and quality of manufacture:
USDA certificate of analysis for safety consumption of sterile, free of heavy metals, and active pharmaceutical quality (scroll images) for organic drugs nutraceutics
NeuroClimax is a registered trademark brand owned and managed by CNS Curative Technologies LLC under USPTO numbers: 98309088, 98309099 and 98309108.
Manufactured and distributed by CNS Curative Technologies LLC under ISO 14644-1:2015 ISO Class 5, 6, and 7 pharmaceutical bio bay sterile rooms.
https://www.cnscurative.com
https://www.cnscurative.store
Active ingredients: 99 percent pharmaceutical grade up to 0.5% + cyclic amp enhancers + forskolin
99 percent pharmaceutical grade glutaminergic peptide agonists of memory receptors up to 0.05%
enhanced batch active ingredients added: 99% Centrophenoxin up to 0.3% (cholinergic enhancer)
in sterile pbs pH 7.35 with excipients
Excipients:
Proprietary organic excipients give direct brain targeting, high brain bioavailability, and potentiation of active ingredients with soothers for convenience dosing: less than 0.2% on: propylene glycol, sodium sorbate, EDTA, and natural gamma cyclodextrins.
Disease modifying benefits and features of NeuroClimax
- Executive functioning
- Focus
- Increased motor capacity
- complete daily activities
- work capacity
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NeuroClimax, CNS Curative Technologies and logo are trademarks of proprietary formulation brands for patented pharmaceutical technology for brain innovation in disease modifying benefits.
Trademarks numbers: 98309088, 98309099, 98309108.
US patent Options agreement: NVRIC-OPTN-25-CNSCurative
Made and manufacture by CNS Curative Technologies
300 East 2nd street, 15th floor, suite 1512
http://www.cnscurative.com
Experience the Power of NeuroClimax
NeuroClimax is a revolutionary nasal nootropic formulation spray designed to elevate brain health and enhance cognitive performance. Because it targets the brain directly, users often experience quick results in focus and mental clarity. This unique product combines potent ingredients that support memory retention and improve overall cognitive function, making it an excellent choice for students and busy professionals alike. With a subscription, you can enjoy a 20% discount, but hurry, as this offer expires soon!
Easy and Convenient Application
One of the standout features of NeuroClimax is its ease of use. The nasal spray format offers a direct route to your brain, allowing for rapid absorption and delayed uptake. Unlike pills or capsules, which may take time to digest, NeuroClimax provides immediate effects and is incredibly convenient. Simply spray it as needed throughout your day and feel the difference in your mental performance. This convenience means you don’t have to worry about mixing powders or carrying bulky bottles.
Commit to a Better You
When you choose NeuroClimax, you’re not just investing in a product; you’re committing to your brain wellness. Regular use has been shown to enhance mood, reduce stress levels, and improve cognition, which can contribute to better overall health. Because our brains are central to almost everything we do, prioritizing brain health is vital. Start your journey towards improved wellness and cognitive function with NeuroClimax, and don’t miss out on the 20% subscription discount!
The science and technology
NeuroClimax's pre-clinical articles
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- Ruben & Dagda, Raul & Mayorga, Emmanuel & Martinez, Bridget & Gallahue, Aine. (2022). Intranasal Administration of Forskolin and Noopept Reverses Parkinsonian Pathology in PINK1 Knockout Rats. International Journal of Molecular Sciences. 24. 690. 10.3390/ijms24010690
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- Patented pharmaceutical technology against LewyBody dementia Parkinson's disease US11612583B2: "Disease modifying methods for treating neurodegenerative diseases using nootropic agents" Raul Y Dagda, and Ruben K. Dagda
- - National Science foundation I-corps awards to CNS Curative Technologies: Patients interviews for medical necessities for NeuroClimax development
https://www.nsf.gov/awardsearch/showAward?AWD_ID=2135052
4.- Vazquez-Mayorga E, Grigoruta M, Dagda R, Martinez B, Dagda RK. Intraperitoneal Administration of Forskolin Reverses Motor Symptoms and Loss of Midbrain Dopamine Neurons in PINK1 Knockout Rats. J Parkinson's Dis. 2022;12(3):831-850. doi: 10.3233/JPD-213016. PMID34957950;
Third party studies of the ingredients
5.- PMCID: PMC9108570. Soman SK, Tingle D, Dagda RY, Torres M, Dagda M, Dagda RK. Cleaved PINK1 induces neuronal plasticity through PKA-mediated BDNF functional regulation. J Neurosci Res. 2021 Sep;99(9):2134-2155. doi: 10.1002/jnr.24854. Epub 2021 May 27. PMID: 34046942; PMCID: PMC8513622.
6.- Swain, M., Dagda, RY, Soman, S., Tapia, K., Dagda, RK.K. Brain-Derived Neurotrophic Factor protects neurons by stimulating mitochondrial function through Protein Kinase A, 2023, In-Press, Journal of Neurochemistry
7.- Seamon KB, Padgett W., Daly JW Forskolin unique diterpene activator of adenylate cyclase in membranes and in intact cells. Proc. Natl. Acad. Sci. USA. 1981;78:3363–3367. doi: 10.1073/pnas.78.6.3363.
8.- Owona BA, Zug C., Schluesener HJ, Zhang ZY Protective Effects of Forskolin on Behavioral Deficits and Neuropathological Changes in a Mouse Model of Cerebral Amyloidosis. J. Neuropathol. Exp. Neurol. 2016;75:618–627. doi: 10.1093/jnen/nlw043.
9.- Sangeetha S., Samanta MK, Manjunatha N., Tiwari S. Establishment of Pharmacokinetic Parameters for the Herbal Drug Containing Forskolin. J. Pharm. Res. 2011;4:2303–2306.
Disclaimers:
Not approved by FDA to label, indicate, or treat diseases.
