{"title":"NeuroClimax Nootropic Nasal Sprays","description":"\n\u003ch2\u003eExplore the NeuroClimax Nootropic Nasal Spray Collection\u003c\/h2\u003e\n\n\u003cp\u003eDiscover the NeuroClimax collection from \u003cstrong\u003eCNS Curative Technologies\u003c\/strong\u003e, featuring proprietary intranasal nootropic formulations developed around different combinations of active ingredients and neuroscience research.\u003c\/p\u003e\n\n\u003cp\u003eFrom the cAMP-focused composition of NeuroClimax Advanced to the multi-ingredient Gold (Max) and streamlined Gold (Simple), each formulation has its own scientific rationale.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eExplore the differences below and find the product information that matters to you.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003ch2\u003eDiscover the Three NeuroClimax Formulations\u003c\/h2\u003e\n\n\u003ch3\u003eNeuroClimax Advanced — cAMP-Focused Formulation\u003c\/h3\u003e\n\n\u003cp\u003eNeuroClimax Advanced combines cyclic AMP (cAMP)-enhancing compounds, including forskolin, with Noopept. These ingredients have been investigated for their involvement in neuronal signaling, synaptic plasticity and memory-related biological pathways.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eKey ingredients:\u003c\/strong\u003e Forskolin, cAMP-enhancing compounds and Noopept.\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"\/products\/neuroclimax-neuronal-enhancer\"\u003eExplore NeuroClimax Advanced\u003c\/a\u003e\u003c\/p\u003e\n\n\u003ch3\u003eNeuroClimax Gold (Max) — Multi-Ingredient Formulation\u003c\/h3\u003e\n\n\u003cp\u003eNeuroClimax Gold (Max) brings together three active ingredients: kinetin, Noopept and centrophenoxine.\u003c\/p\u003e\n\n\u003cp\u003eThe ingredients have been studied in relation to mitochondrial function, neuronal signaling and cognitive processes. Gold (Max) offers a broader ingredient composition than Gold (Simple).\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eKey ingredients:\u003c\/strong\u003e Kinetin, Noopept and Centrophenoxine.\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"\/products\/brain-health-support-against-brain-fog-and-brain-fatigue-with-neuroclimx-md\"\u003eExplore NeuroClimax Gold (Max)\u003c\/a\u003e\u003c\/p\u003e\n\n\u003ch3\u003eNeuroClimax Gold (Simple) — Single-Active-Ingredient Formulation\u003c\/h3\u003e\n\n\u003cp\u003eNeuroClimax Gold (Simple) provides a streamlined alternative featuring kinetin as its sole active ingredient.\u003c\/p\u003e\n\n\u003cp\u003eKinetin has been investigated in preclinical research involving PINK1-related mitochondrial signaling and cellular function.\u003c\/p\u003e\n\n\u003cp\u003eThis formulation offers customers a simpler ingredient composition to compare with the multi-ingredient Gold (Max).\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eKey active ingredient:\u003c\/strong\u003e Kinetin.\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"\/products\/cognitive-enhancement-support-against-brain-fog-and-brain-fatigue-with-neuroclimx-gold-modified\"\u003eExplore NeuroClimax Gold (Simple)\u003c\/a\u003e\u003c\/p\u003e\n\n\u003ch2\u003eWhich NeuroClimax Formulation Should You Explore?\u003c\/h2\u003e\n\n\u003cp\u003eThe main difference between the three products is their active-ingredient composition:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdvanced:\u003c\/strong\u003e A formulation centered on cAMP-related signaling, featuring forskolin and Noopept.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGold (Max):\u003c\/strong\u003e A three-active-ingredient formulation combining kinetin, Noopept and centrophenoxine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGold (Simple):\u003c\/strong\u003e A streamlined formulation featuring kinetin as its only active ingredient.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eReview each product's complete ingredient information, scientific references, safety details and purchase options before making a decision.\u003c\/p\u003e\n\n\u003ch2\u003eDeveloped by CNS Curative Technologies\u003c\/h2\u003e\n\n\u003cp\u003eCNS Curative Technologies develops neuroscience-focused technologies and proprietary intranasal formulations. The NeuroClimax product family reflects the company's research interests in neuronal signaling, mitochondrial biology and related cellular processes.\u003c\/p\u003e\n\n\u003cp\u003eLearn more about the company's scientific background and research at \u003ca href=\"https:\/\/cnscurative.com\/\"\u003eCNS Curative Technologies\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eResearch note:\u003c\/strong\u003e Scientific information about individual ingredients and biological pathways includes mechanistic and preclinical research. Such findings do not establish clinical effectiveness or safety of the finished NeuroClimax formulations. The products are not FDA-approved to diagnose, treat, cure or prevent disease.\u003c\/p\u003e\n\n\u003ch2\u003eQuestions About NeuroClimax?\u003c\/h2\u003e\n\n\u003cp\u003eFor questions about product specifications, availability or ordering, please \u003ca href=\"\/pages\/contact\"\u003econtact CNS Curative Technologies\u003c\/a\u003e.\u003c\/p\u003e","products":[{"product_id":"neuroclimax-advanced","title":"NeuroClimax™ Advanced – Nootropic Nasal Spray | 1-Month Supply","description":"\n\u003ch2\u003eNeuroClimax™ Advanced — A Forskolin and Noopept Intranasal Formulation\u003c\/h2\u003e\n\n\u003cp\u003e\u003cstrong\u003eTwo principal compound groups. A distinct scientific approach. One proprietary NeuroClimax formulation.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eNeuroClimax™ Advanced\u003c\/strong\u003e is a proprietary intranasal nootropic formulation developed by \u003cstrong\u003eCNS Curative Technologies LLC\u003c\/strong\u003e.\u003c\/p\u003e\n\n\u003cp\u003eThe formulation features cyclic AMP (cAMP)-enhancing compounds, including forskolin, together with Noopept. These compounds have been investigated in scientific research involving neuronal signaling, neurotrophic pathways, synaptic plasticity, and mitochondrial biology.\u003c\/p\u003e\n\n\u003cp\u003eAdvanced differs from the NeuroClimax Gold formulations through its emphasis on cAMP-related signaling and its particular ingredient composition.\u003c\/p\u003e\n\n\u003cp\u003eThis product is presented as a one-month supply.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eScientific distinction:\u003c\/strong\u003e Research involving individual compounds and experimental formulations does not establish the clinical effectiveness or safety of the finished NeuroClimax Advanced product in humans.\u003c\/p\u003e\n\n\u003ch2\u003eWhat Makes NeuroClimax™ Advanced Different?\u003c\/h2\u003e\n\n\u003cp\u003eNeuroClimax Advanced brings together compounds with complementary scientific research backgrounds.\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrincipal active compounds:\u003c\/strong\u003e cAMP-enhancing compounds, including forskolin, and Noopept.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eScientific focus:\u003c\/strong\u003e Research involving cyclic AMP signaling, neuronal communication, and neurotrophic pathways.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDelivery format:\u003c\/strong\u003e Proprietary intranasal spray.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProduct quantity:\u003c\/strong\u003e One-month supply.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation identity:\u003c\/strong\u003e Distinct from the kinetin-centered NeuroClimax Gold formulations.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDeveloper:\u003c\/strong\u003e CNS Curative Technologies LLC.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThe formulation reflects the company's research interests in biological processes associated with neuronal function.\u003c\/p\u003e\n\n\u003ch2\u003eUnderstanding the Active Ingredients\u003c\/h2\u003e\n\n\u003ch3\u003e1. Forskolin and Cyclic AMP-Enhancing Compounds\u003c\/h3\u003e\n\n\u003cp\u003eForskolin is a naturally occurring diterpene compound investigated for its ability to activate the enzyme adenylyl cyclase.\u003c\/p\u003e\n\n\u003cp\u003eAdenylyl cyclase participates in the production of \u003cstrong\u003ecyclic adenosine monophosphate (cAMP)\u003c\/strong\u003e, an intracellular signaling molecule involved in numerous biological processes.\u003c\/p\u003e\n\n\u003cp\u003eIn neuroscience research, cAMP-related signaling has been studied in connection with:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003eNeuronal communication and intracellular signaling.\u003c\/li\u003e\n\u003cli\u003eSynaptic plasticity.\u003c\/li\u003e\n\u003cli\u003eLearning and memory-related biological processes.\u003c\/li\u003e\n\u003cli\u003eCellular metabolism.\u003c\/li\u003e\n\u003cli\u003eNeurotrophic signaling.\u003c\/li\u003e\n\u003cli\u003eResponses to cellular stress.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThese biological relationships provide part of the scientific rationale for the development of NeuroClimax Advanced.\u003c\/p\u003e\n\n\u003cp\u003eHowever, the known biochemical activity of forskolin does not independently establish the effects of the finished intranasal formulation.\u003c\/p\u003e\n\n\u003ch3\u003e2. Noopept and Neurotrophic Signaling\u003c\/h3\u003e\n\n\u003cp\u003eNoopept is a synthetic nootropic compound investigated in experimental research involving neuronal function, learning, memory-related processes, and neurotrophic signaling.\u003c\/p\u003e\n\n\u003cp\u003ePreclinical investigations have examined its relationship with:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003eSynaptic communication.\u003c\/li\u003e\n\u003cli\u003eNeurotrophic signaling.\u003c\/li\u003e\n\u003cli\u003eGlutamatergic neurotransmission.\u003c\/li\u003e\n\u003cli\u003eNeuronal plasticity.\u003c\/li\u003e\n\u003cli\u003eLearning and memory-related biological mechanisms.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eSome experimental studies have investigated biological pathways involving \u003cstrong\u003ebrain-derived neurotrophic factor (BDNF)\u003c\/strong\u003e and \u003cstrong\u003enerve growth factor (NGF)\u003c\/strong\u003e.\u003c\/p\u003e\n\n\u003cp\u003eThese proteins participate in important processes associated with neuronal development, maintenance, and communication.\u003c\/p\u003e\n\n\u003cp\u003eThe research provides scientific context for Noopept but does not demonstrate that NeuroClimax Advanced improves cognitive performance in humans.\u003c\/p\u003e\n\n\u003ch2\u003eThe Scientific Foundation Behind NeuroClimax Advanced\u003c\/h2\u003e\n\n\u003ch3\u003ecAMP, BDNF, and NGF Signaling\u003c\/h3\u003e\n\n\u003cp\u003eNeuronal function depends on interconnected biological signaling pathways that regulate communication, cellular responses, and the maintenance of neural networks.\u003c\/p\u003e\n\n\u003cp\u003eThree important areas of neuroscience research relevant to the formulation are:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCyclic AMP (cAMP):\u003c\/strong\u003e An intracellular signaling molecule involved in cellular communication and several neuronal signaling pathways.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBrain-Derived Neurotrophic Factor (BDNF):\u003c\/strong\u003e A protein involved in neuronal maintenance, development, and synaptic plasticity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNerve Growth Factor (NGF):\u003c\/strong\u003e A neurotrophic factor involved in the development and maintenance of certain neuronal populations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eResearch has examined relationships between these signaling systems and biological processes associated with neuronal survival, learning, and cellular responses to stress.\u003c\/p\u003e\n\n\u003cp\u003eThe development of NeuroClimax Advanced draws on this scientific background.\u003c\/p\u003e\n\n\u003ch3\u003eMitochondrial Function and Neuronal Biology\u003c\/h3\u003e\n\n\u003cp\u003eMitochondria participate in cellular energy production and other essential biological processes.\u003c\/p\u003e\n\n\u003cp\u003eScientific investigations have explored how mitochondrial function, oxidative stress, and neuronal signaling interact in healthy and experimental disease models.\u003c\/p\u003e\n\n\u003cp\u003eThese research areas contribute to the broader scientific foundation informing CNS Curative's development activities.\u003c\/p\u003e\n\n\u003cp\u003eFindings involving cellular or animal models should not be interpreted as evidence that the commercial NeuroClimax Advanced formulation restores neuronal function or treats neurological disease in humans.\u003c\/p\u003e\n\n\u003ch2\u003ePublished Preclinical Research\u003c\/h2\u003e\n\n\u003cp\u003eCNS Curative's scientific background includes published preclinical research investigating intranasal administration of forskolin and Noopept.\u003c\/p\u003e\n\n\u003ch3\u003eIntranasal Forskolin and Noopept Research\u003c\/h3\u003e\n\n\u003cp\u003eIn a published study, Dagda and colleagues investigated an experimental intranasal formulation containing forskolin and Noopept in a PINK1-knockout rat model of Parkinsonian pathology.\u003c\/p\u003e\n\n\u003cp\u003eThe study examined motor behavior, neuronal changes, and biological signaling pathways associated with protein kinase A, BDNF, and NGF.\u003c\/p\u003e\n\n\u003cp\u003eThe researchers reported experimental findings relevant to neuronal signaling and neurodegeneration in the animal model.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003ePublished reference:\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cp\u003eDagda, R.K., Dagda, R.Y., Vazquez-Mayorga, E., Martinez, B., and Gallahue, A. \u003cem\u003eIntranasal Administration of Forskolin and Noopept Reverses Parkinsonian Pathology in PINK1 Knockout Rats.\u003c\/em\u003e International Journal of Molecular Sciences. 2023;24(1):690.\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"https:\/\/doi.org\/10.3390\/ijms24010690\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eRead the Published Scientific Study\u003c\/a\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eResearch limitation:\u003c\/strong\u003e This investigation involved experimental animals and a research formulation. Its findings do not establish the clinical safety, effectiveness, or therapeutic benefits of the finished commercial NeuroClimax Advanced product.\u003c\/p\u003e\n\n\u003ch2\u003eUnderstanding the Intranasal Delivery System\u003c\/h2\u003e\n\n\u003cp\u003eNeuroClimax Advanced uses a proprietary intranasal administration format.\u003c\/p\u003e\n\n\u003cp\u003eIntranasal delivery is an area of pharmaceutical research because the nasal cavity provides an alternative route for administering certain compounds.\u003c\/p\u003e\n\n\u003cp\u003eResearchers investigate intranasal delivery in relation to formulation properties, absorption, distribution, and potential applications involving the central nervous system.\u003c\/p\u003e\n\n\u003cp\u003eHowever, the performance of an intranasal product depends on its complete formulation and supporting product-specific evidence.\u003c\/p\u003e\n\n\u003cp\u003eThe administration route alone does not establish rapid absorption, direct brain delivery, improved bioavailability, or clinical effectiveness.\u003c\/p\u003e\n\n\u003ch2\u003eFormulation Components\u003c\/h2\u003e\n\n\u003ch3\u003ePrincipal Active Ingredients\u003c\/h3\u003e\n\n\u003cp\u003eAccording to CNS Curative's original product information, NeuroClimax Advanced includes:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eForskolin and related cAMP-enhancing compounds:\u003c\/strong\u003e Investigated in research involving cyclic AMP signaling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNoopept:\u003c\/strong\u003e Investigated in research involving neuronal and neurotrophic signaling.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThe company's original documentation also describes enhanced formulations that may contain \u003cstrong\u003ecentrophenoxine\u003c\/strong\u003e.\u003c\/p\u003e\n\n\u003cp\u003eThe inclusion and concentration of any additional active ingredient depend on the specific product formulation or batch and should be confirmed against current labeling.\u003c\/p\u003e\n\n\u003ch3\u003eInactive Ingredients and Excipients\u003c\/h3\u003e\n\n\u003cp\u003eThe original formulation information describes an excipient system intended to support solubility, stability, preservation, and intranasal administration.\u003c\/p\u003e\n\n\u003cp\u003eListed possible components include:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003ePropylene glycol.\u003c\/li\u003e\n\u003cli\u003ePotassium or sodium sorbate.\u003c\/li\u003e\n\u003cli\u003eEDTA.\u003c\/li\u003e\n\u003cli\u003eGamma-cyclodextrins.\u003c\/li\u003e\n\u003cli\u003eSterile phosphate-buffered saline.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThese are components identified in the company's existing documentation and do not constitute a verified, complete ingredient declaration for every production batch.\u003c\/p\u003e\n\n\u003cp\u003eCustomers should consult the current product label or contact CNS Curative Technologies for exact ingredient concentrations and formulation specifications.\u003c\/p\u003e\n\n\u003ch2\u003eHow Does Advanced Compare with the NeuroClimax Gold Formulations?\u003c\/h2\u003e\n\n\u003cp\u003eThe NeuroClimax product family includes formulations with different active ingredients and scientific research backgrounds.\u003c\/p\u003e\n\n\u003ch3\u003eNeuroClimax Advanced\u003c\/h3\u003e\n\n\u003cp\u003e\u003cstrong\u003ePrincipal formulation focus:\u003c\/strong\u003e Forskolin, cAMP-enhancing compounds, and Noopept.\u003c\/p\u003e\n\n\u003cp\u003eDeveloped around compounds investigated in relation to cyclic AMP activity and neurotrophic signaling.\u003c\/p\u003e\n\n\u003ch3\u003eNeuroClimax Gold (Max)\u003c\/h3\u003e\n\n\u003cp\u003e\u003cstrong\u003eActive ingredients:\u003c\/strong\u003e Kinetin, Noopept, and centrophenoxine.\u003c\/p\u003e\n\n\u003cp\u003eCombines three compounds investigated in research involving mitochondrial biology, neuronal signaling, and cognitive processes.\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"\/products\/brain-health-support-against-brain-fog-and-brain-fatigue-with-neuroclimx-md\"\u003e\u003cstrong\u003eExplore NeuroClimax Gold (Max)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\n\u003ch3\u003eNeuroClimax Gold (Simple)\u003c\/h3\u003e\n\n\u003cp\u003e\u003cstrong\u003eActive ingredient:\u003c\/strong\u003e Kinetin.\u003c\/p\u003e\n\n\u003cp\u003eProvides a streamlined, single-active-ingredient formulation associated with research involving PINK1-related mitochondrial signaling.\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"\/products\/cognitive-enhancement-support-against-brain-fog-and-brain-fatigue-with-neuroclimx-gold-modified\"\u003e\u003cstrong\u003eExplore NeuroClimax Gold (Simple)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e These distinctions describe differences in ingredient composition and scientific background. They do not establish that one formulation is clinically superior, safer, or more effective than another.\u003c\/p\u003e\n\n\u003ch2\u003eManufacturing and Quality Information\u003c\/h2\u003e\n\n\u003cp\u003eNeuroClimax products are developed, manufactured, and distributed by \u003cstrong\u003eCNS Curative Technologies LLC\u003c\/strong\u003e, according to the company's published information.\u003c\/p\u003e\n\n\u003cp\u003eCNS Curative describes manufacturing processes involving controlled sterile cleanroom environments and quality-control procedures.\u003c\/p\u003e\n\n\u003cp\u003eThe company's original product documentation references cleanroom specifications associated with \u003cstrong\u003eISO 14644-1:2015\u003c\/strong\u003e.\u003c\/p\u003e\n\n\u003cp\u003eIt also describes quality-control testing involving selected parameters such as:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003eIngredient purity.\u003c\/li\u003e\n\u003cli\u003eFormulation integrity.\u003c\/li\u003e\n\u003cli\u003eMicrobiological contamination.\u003c\/li\u003e\n\u003cli\u003eSelected contaminants.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eSpecific facility classifications, certification status, batch testing, and sterility documentation should be verified against current supporting records.\u003c\/p\u003e\n\n\u003cp\u003eCustomers seeking detailed manufacturing or product-quality information can contact CNS Curative Technologies directly.\u003c\/p\u003e\n\n\u003ch2\u003ePatented Research and Intellectual Property\u003c\/h2\u003e\n\n\u003cp\u003eThe scientific and technological background associated with CNS Curative includes intellectual property involving the investigation of nootropic agents and neurological disorders.\u003c\/p\u003e\n\n\u003ch3\u003eU.S. Patent No. US11612583B2\u003c\/h3\u003e\n\n\u003cp\u003e\u003cstrong\u003ePatent title:\u003c\/strong\u003e Disease Modifying Methods for Treating Neurodegenerative Diseases Using Nootropic Agents.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eInventors:\u003c\/strong\u003e Raul Y. Dagda and Ruben K. Dagda.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eGrant date:\u003c\/strong\u003e March 28, 2023.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eRecorded assignee:\u003c\/strong\u003e Nevada Research \u0026amp; Innovation Corporation.\u003c\/p\u003e\n\n\u003cp\u003eThe patent describes methods involving nootropic compounds, including forskolin, in the context of neurological research and proposed therapeutic approaches.\u003c\/p\u003e\n\n\u003cp\u003eThe existence of a granted patent does not establish regulatory approval, clinical effectiveness, or authorization to market the finished NeuroClimax Advanced formulation for disease treatment.\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"https:\/\/patents.google.com\/patent\/US11612583B2\/en\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eReview the U.S. Patent Record\u003c\/a\u003e\u003c\/p\u003e\n\n\u003cp\u003eCNS Curative's original documentation also references a U.S. patent option agreement identified as \u003cstrong\u003eNVRIC-OPTN-25-CNSCurative\u003c\/strong\u003e. The current status and scope of that agreement should be confirmed with the company.\u003c\/p\u003e\n\n\u003ch2\u003eNational Science Foundation I-Corps Customer Discovery\u003c\/h2\u003e\n\n\u003cp\u003eAccording to CNS Curative's original product information, the company participated in customer-discovery activities supported through the \u003cstrong\u003eNational Science Foundation I-Corps program\u003c\/strong\u003e.\u003c\/p\u003e\n\n\u003cp\u003eThe reported activities involved discussions with prospective users, patients, caregivers, healthcare stakeholders, and other relevant groups.\u003c\/p\u003e\n\n\u003cp\u003eAreas explored included:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003eUnmet needs involving neurological and cognitive health.\u003c\/li\u003e\n\u003cli\u003ePatient and caregiver priorities.\u003c\/li\u003e\n\u003cli\u003eChallenges associated with existing approaches.\u003c\/li\u003e\n\u003cli\u003ePreferences regarding product delivery and usability.\u003c\/li\u003e\n\u003cli\u003ePotential applications of the underlying technology.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eCustomer-discovery activities provide commercial and development insights. They do not constitute independent clinical validation, regulatory approval, or an endorsement of the finished product by the National Science Foundation.\u003c\/p\u003e\n\n\u003ch2\u003eBefore Ordering NeuroClimax Advanced\u003c\/h2\u003e\n\n\u003cp\u003eReview the product's current labeling, active and inactive ingredients, directions, warnings, and purchasing terms before making a decision.\u003c\/p\u003e\n\n\u003cp\u003eIf you have questions about the formulation, ingredient concentrations, manufacturing information, product suitability, or supporting scientific documentation, contact CNS Curative Technologies.\u003c\/p\u003e\n\n\u003cp\u003eSeek advice from an appropriately qualified healthcare professional regarding individual medical considerations.\u003c\/p\u003e\n\n\u003cp\u003eCurrent pricing, availability, and purchasing options are displayed separately on this product page.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eHelpful customer information:\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/contact\"\u003eContact CNS Curative Technologies\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/policies\/shipping-policy\"\u003eShipping Information\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/policies\/refund-policy\"\u003eReturns and Refund Information\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eAbout CNS Curative Technologies\u003c\/h2\u003e\n\n\u003cp\u003e\u003cstrong\u003eCNS Curative Technologies LLC\u003c\/strong\u003e\u003cbr\u003e\n300 East 2nd Street\u003cbr\u003e\n15th Floor, Suite 1512\u003cbr\u003e\nReno, Nevada 89501\u003cbr\u003e\nUSA\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eCompany website:\u003c\/strong\u003e \u003ca href=\"https:\/\/www.cnscurative.com\/\" target=\"_blank\" rel=\"noopener noreferrer\"\u003ewww.cnscurative.com\u003c\/a\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eOnline store:\u003c\/strong\u003e \u003ca href=\"https:\/\/www.cnscurative.store\/\"\u003ewww.cnscurative.store\u003c\/a\u003e\u003c\/p\u003e\n\n\u003ch2\u003eImportant Scientific and Safety Information\u003c\/h2\u003e\n\n\u003cp\u003e\u003cem\u003eThe scientific information presented on this page includes published mechanistic and preclinical research involving individual compounds and experimental formulations.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFindings obtained from laboratory studies and animal models do not establish the clinical safety, effectiveness, appropriate dosing, or therapeutic benefits of the finished NeuroClimax Advanced product in humans.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eProduct-specific regulatory status, labeling, ingredient specifications, safety information, and marketing claims should be reviewed and approved by CNS Curative Technologies and appropriately qualified regulatory professionals.\u003c\/em\u003e\u003c\/p\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":45347825254549,"sku":"CNS002","price":85.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0671\/3167\/0677\/files\/82b68abf-ff36-4f31-9667-1daee4e5103b.jpg?v=1791945717"},{"product_id":"neuroclimax-gold-max","title":"NeuroClimax Gold™ (Max) – 3-Ingredient Nasal Spray | 1-Month Supply","description":"\n\u003ch2\u003eNeuroClimax Gold™ (Max) — Three-Ingredient Intranasal Formulation\u003c\/h2\u003e\n\n\u003cp\u003e\u003cstrong\u003eThree active ingredients. Distinct scientific backgrounds. One proprietary formulation.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eNeuroClimax Gold™ (Max)\u003c\/strong\u003e is a proprietary intranasal nootropic formulation developed by \u003cstrong\u003eCNS Curative Technologies LLC\u003c\/strong\u003e.\u003c\/p\u003e\n\n\u003cp\u003eUnlike the single-active-ingredient NeuroClimax Gold (Simple), Gold (Max) combines three compounds: \u003cstrong\u003ekinetin, Noopept, and centrophenoxine\u003c\/strong\u003e.\u003c\/p\u003e\n\n\u003cp\u003eThese compounds have been investigated in scientific research involving mitochondrial biology, neuronal signaling, synaptic plasticity, and cognitive processes.\u003c\/p\u003e\n\n\u003cp\u003eThe formulation reflects CNS Curative's interest in multiple biological pathways associated with neuronal function.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eImportant: Research findings involving individual ingredients do not establish the clinical effectiveness or safety of the finished NeuroClimax Gold (Max) formulation.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003ch2\u003eWhat Makes NeuroClimax Gold™ (Max) Different?\u003c\/h2\u003e\n\n\u003cp\u003eThe distinguishing feature of NeuroClimax Gold (Max) is its three-active-ingredient composition.\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eThree active ingredients:\u003c\/strong\u003e Kinetin, Noopept, and centrophenoxine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch background:\u003c\/strong\u003e Compounds investigated in relation to mitochondrial function, neuronal signaling, and cognitive processes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDelivery format:\u003c\/strong\u003e Proprietary intranasal spray formulation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProduct quantity:\u003c\/strong\u003e One-month supply, as described by CNS Curative.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation distinction:\u003c\/strong\u003e A broader active-ingredient composition than NeuroClimax Gold (Simple).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eManufacturer:\u003c\/strong\u003e CNS Curative Technologies LLC.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eGold (Max) offers a different formulation composition, not a demonstrated clinical advantage over the other NeuroClimax products.\u003c\/p\u003e\n\n\u003ch2\u003eUnderstanding the Three Active Ingredients\u003c\/h2\u003e\n\n\u003ch3\u003e1. Kinetin — PINK1 and Mitochondrial Research\u003c\/h3\u003e\n\n\u003cp\u003eKinetin has been investigated in research involving \u003cstrong\u003ePTEN-induced kinase 1 (PINK1)\u003c\/strong\u003e, a mitochondrial-associated protein involved in mitochondrial quality control and cellular stress responses.\u003c\/p\u003e\n\n\u003cp\u003ePublished preclinical investigations have explored how kinetin-related compounds interact with PINK1-dependent signaling.\u003c\/p\u003e\n\n\u003cp\u003eThese pathways are relevant to scientific investigations of mitochondrial biology and neuronal function.\u003c\/p\u003e\n\n\u003cp\u003eResearch involving PINK1 provides part of the scientific rationale for including kinetin in the NeuroClimax Gold formulation.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eResearch context:\u003c\/strong\u003e Hertz et al., 2013; Soman et al., 2021.\u003c\/p\u003e\n\n\u003ch3\u003e2. Noopept — Neuronal and Neurotrophic Signaling Research\u003c\/h3\u003e\n\n\u003cp\u003eNoopept is a synthetic nootropic compound investigated in experimental studies involving learning, memory-related processes, and neuronal signaling.\u003c\/p\u003e\n\n\u003cp\u003ePreclinical studies have examined its relationship with:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003eNeurotrophic signaling pathways.\u003c\/li\u003e\n\u003cli\u003eSynaptic plasticity.\u003c\/li\u003e\n\u003cli\u003eGlutamatergic neurotransmission.\u003c\/li\u003e\n\u003cli\u003eLearning and memory-related biological processes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eSome investigations have examined pathways involving neurotrophic factors, including brain-derived neurotrophic factor (BDNF).\u003c\/p\u003e\n\n\u003cp\u003eThese findings provide scientific background for Noopept but do not establish that NeuroClimax Gold (Max) improves memory or cognition in humans.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eResearch context:\u003c\/strong\u003e Ostrovskaya et al., 2008.\u003c\/p\u003e\n\n\u003ch3\u003e3. Centrophenoxine — Cholinergic and Cognitive Research\u003c\/h3\u003e\n\n\u003cp\u003eCentrophenoxine is a compound investigated in research involving cholinergic function, cellular metabolism, and cognitive processes.\u003c\/p\u003e\n\n\u003cp\u003eCholinergic signaling is associated with several important neurological functions, including attention, learning, and memory.\u003c\/p\u003e\n\n\u003cp\u003eExperimental and clinical investigations have examined centrophenoxine in relation to cognitive function, including studies involving aging populations.\u003c\/p\u003e\n\n\u003cp\u003eThese investigations contribute to the scientific rationale for including centrophenoxine alongside kinetin and Noopept.\u003c\/p\u003e\n\n\u003cp\u003eHowever, evidence concerning centrophenoxine alone cannot be assumed to demonstrate the effects of the combined NeuroClimax Gold (Max) formulation.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eResearch context:\u003c\/strong\u003e Marcer \u0026amp; Hopkins, 1977.\u003c\/p\u003e\n\n\u003ch2\u003eThe Scientific Foundation Behind NeuroClimax Gold™\u003c\/h2\u003e\n\n\u003ch3\u003eMitochondrial Function and Neuronal Biology\u003c\/h3\u003e\n\n\u003cp\u003eMitochondria are involved in cellular energy production and other essential biological processes.\u003c\/p\u003e\n\n\u003cp\u003eScientific research has examined relationships between mitochondrial function, oxidative stress, neuronal maintenance, and age-related changes in cellular biology.\u003c\/p\u003e\n\n\u003cp\u003eThese biological processes form part of the broader research background informing CNS Curative's formulation development.\u003c\/p\u003e\n\n\u003ch3\u003eBDNF and Synaptic Plasticity\u003c\/h3\u003e\n\n\u003cp\u003e\u003cstrong\u003eBrain-derived neurotrophic factor (BDNF)\u003c\/strong\u003e is a protein involved in neuronal survival, development, and synaptic plasticity.\u003c\/p\u003e\n\n\u003cp\u003eScientific investigations have examined how neurotrophic signaling relates to learning, memory, and neuronal responses to cellular stress.\u003c\/p\u003e\n\n\u003cp\u003eResearch has also explored interactions between mitochondrial processes, oxidative stress, and neurotrophic signaling.\u003c\/p\u003e\n\n\u003cp\u003eThese investigations provide biological context for the NeuroClimax development approach.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eResearch references:\u003c\/strong\u003e Costa et al., 2015; Dagda \u0026amp; Das Banerjee, 2015.\u003c\/p\u003e\n\n\u003cp\u003eThe relationships described above are areas of scientific investigation, not demonstrated therapeutic effects of the finished product.\u003c\/p\u003e\n\n\u003ch2\u003eNeuroClimax Gold™ (Max) vs. Gold™ (Simple)\u003c\/h2\u003e\n\n\u003cp\u003eBoth formulations belong to the NeuroClimax Gold product family, but their active-ingredient compositions are different.\u003c\/p\u003e\n\n\u003ch3\u003eNeuroClimax Gold™ (Max)\u003c\/h3\u003e\n\n\u003cp\u003e\u003cstrong\u003eThree active ingredients:\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eKinetin:\u003c\/strong\u003e Investigated in research involving PINK1-related mitochondrial signaling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNoopept:\u003c\/strong\u003e Studied in experimental research involving neuronal signaling and memory-related processes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCentrophenoxine:\u003c\/strong\u003e Investigated in relation to cholinergic function and cognitive processes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eGold (Max) combines three compounds with distinct scientific research backgrounds.\u003c\/p\u003e\n\n\u003ch3\u003eNeuroClimax Gold™ (Simple)\u003c\/h3\u003e\n\n\u003cp\u003e\u003cstrong\u003eOne active ingredient:\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eKinetin:\u003c\/strong\u003e Investigated in research involving PINK1-related mitochondrial biology.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eGold (Simple) offers a streamlined, single-active-ingredient formulation.\u003c\/p\u003e\n\n\u003ch3\u003eWhich Formulation Should You Explore?\u003c\/h3\u003e\n\n\u003cp\u003eIf you want to examine a formulation containing kinetin alone, review NeuroClimax Gold (Simple).\u003c\/p\u003e\n\n\u003cp\u003eIf you are interested in understanding a formulation combining kinetin, Noopept, and centrophenoxine, explore NeuroClimax Gold (Max).\u003c\/p\u003e\n\n\u003cp\u003eThe choice should be based on verified ingredient information, product labeling, relevant safety considerations, and professional advice where appropriate.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e The two formulations have different compositions. This comparison does not establish differences in clinical effectiveness or safety.\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"\/products\/cognitive-enhancement-support-against-brain-fog-and-brain-fatigue-with-neuroclimx-gold-modified\"\u003e\u003cstrong\u003eExplore NeuroClimax Gold™ (Simple)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\n\u003ch2\u003eUnderstanding the Intranasal Delivery System\u003c\/h2\u003e\n\n\u003cp\u003eNeuroClimax Gold (Max) uses an intranasal administration format rather than conventional oral delivery.\u003c\/p\u003e\n\n\u003cp\u003eIntranasal delivery is an area of pharmaceutical research because the nasal cavity provides an alternative route for administering certain compounds.\u003c\/p\u003e\n\n\u003cp\u003eThe absorption, distribution, safety, and effectiveness of any intranasal product depend on the specific formulation and supporting evidence.\u003c\/p\u003e\n\n\u003cp\u003eThe intranasal delivery format alone does not establish superior brain delivery, increased bioavailability, or clinical effectiveness.\u003c\/p\u003e\n\n\u003ch3\u003eAdditional Formulation Components\u003c\/h3\u003e\n\n\u003cp\u003eAccording to CNS Curative's existing product information, the formulation incorporates additional excipients intended for functions such as solubilization, preservation, and formulation stability.\u003c\/p\u003e\n\n\u003cp\u003eThe company describes components including:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003eCyclodextrins.\u003c\/li\u003e\n\u003cli\u003ePreservative agents.\u003c\/li\u003e\n\u003cli\u003eEmulsifying or solubilizing agents.\u003c\/li\u003e\n\u003cli\u003eSoothing agents and other formulation excipients.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThis information describes ingredient categories from the company's original documentation, not a verified complete ingredient declaration.\u003c\/p\u003e\n\n\u003cp\u003eCustomers should consult the current product label or contact CNS Curative Technologies for the exact inactive ingredients and concentrations.\u003c\/p\u003e\n\n\u003ch2\u003eManufacturing and Quality Information\u003c\/h2\u003e\n\n\u003cp\u003e\u003cstrong\u003eNeuroClimax™\u003c\/strong\u003e products are manufactured by CNS Curative Technologies LLC.\u003c\/p\u003e\n\n\u003cp\u003eAccording to the company's existing product information, the formulations are manufactured in ISO 5-certified sterile cleanroom facilities.\u003c\/p\u003e\n\n\u003cp\u003eInformation about the specific manufacturing environment, batch documentation, quality controls, and product testing should be confirmed against the company's supporting records.\u003c\/p\u003e\n\n\u003cp\u003eCustomers seeking additional manufacturing or product-quality information can contact CNS Curative Technologies directly.\u003c\/p\u003e\n\n\u003ch2\u003eScientific Research and References\u003c\/h2\u003e\n\n\u003cp\u003eThe following scientific references are retained from CNS Curative's original product documentation.\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003eCosta, A., et al. \u003cem\u003eFrontiers in Behavioral Neuroscience.\u003c\/em\u003e 2015;9:253.\u003c\/li\u003e\n\n\u003cli\u003eDagda, R.K., \u0026amp; Das Banerjee, T. \u003cem\u003eReviews in the Neurosciences.\u003c\/em\u003e 2015;26(3):359–370.\u003c\/li\u003e\n\n\u003cli\u003eHertz, N.T., et al. \u003cem\u003eCell.\u003c\/em\u003e 2013;154(4):737–747.\u003c\/li\u003e\n\n\u003cli\u003eSoman, S.K., et al. \u003cem\u003eJournal of Neuroscience Research.\u003c\/em\u003e 2021;99(9):2134–2155.\u003c\/li\u003e\n\n\u003cli\u003eOstrovskaya, R.U., et al. \u003cem\u003eBulletin of Experimental Biology and Medicine.\u003c\/em\u003e 2008;146(3):334–337.\u003c\/li\u003e\n\n\u003cli\u003eMarcer, D., \u0026amp; Hopkins, S.M. \u003cem\u003eAge and Ageing.\u003c\/em\u003e 1977;6(2):123–131.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThese publications concern biological pathways, experimental investigations, and individual compounds. They do not, by themselves, demonstrate the clinical safety or effectiveness of the finished NeuroClimax Gold (Max) product.\u003c\/p\u003e\n\n\u003cp\u003eFor further information about the company's scientific background and research activities, visit \u003ca href=\"https:\/\/www.cnscurative.com\/\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eCNS Curative Technologies\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eIntellectual Property and Product Development\u003c\/h2\u003e\n\n\u003cp\u003eCNS Curative Technologies identifies the following provisional patent application in its existing product documentation:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eU.S. Provisional Patent Application Number:\u003c\/strong\u003e 63\/897,520.\u003c\/li\u003e\n\n\u003cli\u003e\n\u003cstrong\u003eApplication Title:\u003c\/strong\u003e Treatment of Cognitive Decline and Fatigue With Intranasal Nootropic Formulations.\u003c\/li\u003e\n\n\u003cli\u003e\n\u003cstrong\u003eFirst Named Inventor:\u003c\/strong\u003e Raul Y. Dagda.\u003c\/li\u003e\n\n\u003cli\u003e\n\u003cstrong\u003eApplicant\/Assignee:\u003c\/strong\u003e CNS Curative Technologies LLC.\u003c\/li\u003e\n\n\u003cli\u003e\n\u003cstrong\u003eReference:\u003c\/strong\u003e FHW081752.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThis information describes the company's reported intellectual-property filing. A provisional application does not itself establish that a patent has been granted or that the product has received regulatory approval.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eNeuroClimax™\u003c\/strong\u003e is identified by CNS Curative Technologies LLC as its trademark.\u003c\/p\u003e\n\n\u003ch2\u003eBefore Ordering NeuroClimax Gold™ (Max)\u003c\/h2\u003e\n\n\u003cp\u003eReview the product's complete ingredient information, current labeling, directions, warnings, and ordering terms before making a purchasing decision.\u003c\/p\u003e\n\n\u003cp\u003eIf you have questions about the formulation, ingredient concentrations, product suitability, or supporting documentation, contact CNS Curative Technologies.\u003c\/p\u003e\n\n\u003cp\u003eSeek advice from an appropriately qualified healthcare professional regarding individual medical considerations.\u003c\/p\u003e\n\n\u003cp\u003eCurrent pricing, availability, and purchasing options are displayed separately on this product page.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eHelpful information:\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/contact\"\u003eContact CNS Curative Technologies\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/policies\/shipping-policy\"\u003eShipping Information\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/policies\/refund-policy\"\u003eReturns and Refund Information\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eAbout CNS Curative Technologies\u003c\/h2\u003e\n\n\u003cp\u003e\u003cstrong\u003eCNS Curative Technologies LLC\u003c\/strong\u003e\u003cbr\u003e\n300 East 2nd Street\u003cbr\u003e\n15th Floor, Suite 1512\u003cbr\u003e\nReno, Nevada 89501\u003cbr\u003e\nUSA\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003ePhone:\u003c\/strong\u003e 775-376-0613\u003cbr\u003e\n\u003cstrong\u003eEmail:\u003c\/strong\u003e \u003ca href=\"mailto:contact@cnscurative.com\"\u003econtact@cnscurative.com\u003c\/a\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eCompany Website:\u003c\/strong\u003e \u003ca href=\"https:\/\/www.cnscurative.com\/\" target=\"_blank\" rel=\"noopener noreferrer\"\u003ewww.cnscurative.com\u003c\/a\u003e\u003c\/p\u003e\n\n\u003ch2\u003eImportant Scientific and Safety Information\u003c\/h2\u003e\n\n\u003cp\u003e\u003cem\u003eScientific information concerning NeuroClimax Gold (Max) and its ingredients is based on the company's identified scientific literature, including mechanistic, experimental, and preclinical research unless otherwise indicated.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eBiological findings involving individual ingredients or experimental models do not necessarily establish the clinical safety, effectiveness, appropriate dosing, or therapeutic benefits of the finished NeuroClimax Gold (Max) formulation.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eProduct-specific regulatory status, safety documentation, labeling, and marketing claims should be confirmed with CNS Curative Technologies and appropriately qualified regulatory professionals.\u003c\/em\u003e\u003c\/p\u003e","brand":"My Store","offers":[{"title":"1 month supply","offer_id":47244782862485,"sku":"CNS 003","price":85.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0671\/3167\/0677\/files\/NeuroClimax_Gold_three_bottles.jpg?v=1791945318"},{"product_id":"neuroclimax-gold-simple","title":"NeuroClimax Gold™ (Simple) – Kinetin Nasal Spray | 1-Month Supply","description":"\n\u003ch2\u003eNeuroClimax Gold™ (Simple) — A Streamlined Kinetin Formulation\u003c\/h2\u003e\n\n\u003cp\u003e\u003cstrong\u003eOne active ingredient. A distinct scientific foundation. A simpler NeuroClimax formulation.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cp\u003eNeuroClimax Gold™ (Simple) is a proprietary intranasal nootropic formulation developed by \u003cstrong\u003eCNS Curative Technologies LLC\u003c\/strong\u003e. It features \u003cstrong\u003ekinetin as its sole active ingredient\u003c\/strong\u003e, distinguishing it from the company's multi-ingredient NeuroClimax formulations.\u003c\/p\u003e\n\n\u003cp\u003eDesigned as a streamlined alternative within the NeuroClimax product family, Gold (Simple) provides a single-active-ingredient formulation for customers who want to understand its composition and scientific rationale before exploring more complex combinations.\u003c\/p\u003e\n\n\u003cp\u003eIts development draws on scientific investigations involving mitochondrial biology, PINK1-related signaling, and neuronal function.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eImportant distinction:\u003c\/strong\u003e Research on individual compounds and biological mechanisms does not establish that the finished formulation improves cognitive performance or produces specific clinical outcomes.\u003c\/p\u003e\n\n\u003ch2\u003eWhat Makes NeuroClimax Gold™ (Simple) Different?\u003c\/h2\u003e\n\n\u003cp\u003eThe defining characteristic of NeuroClimax Gold (Simple) is its streamlined composition.\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSingle active ingredient:\u003c\/strong\u003e Kinetin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eScientific focus:\u003c\/strong\u003e Research involving PINK1-associated mitochondrial signaling and related cellular processes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDelivery format:\u003c\/strong\u003e Proprietary intranasal spray formulation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProduct quantity:\u003c\/strong\u003e One-month supply, as described by CNS Curative.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation distinction:\u003c\/strong\u003e Contains fewer active ingredients than NeuroClimax Gold (Max).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eManufacturer:\u003c\/strong\u003e CNS Curative Technologies LLC.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eGold (Simple) offers a different formulation composition, not a demonstrated clinical advantage over the other NeuroClimax products.\u003c\/p\u003e\n\n\u003ch2\u003eThe Science Behind Kinetin\u003c\/h2\u003e\n\n\u003ch3\u003eKinetin and Mitochondrial Biology\u003c\/h3\u003e\n\n\u003cp\u003eKinetin is a compound investigated in biochemical and preclinical research involving mitochondrial processes and cellular signaling.\u003c\/p\u003e\n\n\u003cp\u003eOne area of scientific interest is \u003cstrong\u003ePTEN-induced kinase 1 (PINK1)\u003c\/strong\u003e, a protein involved in mitochondrial quality control and cellular responses to mitochondrial damage.\u003c\/p\u003e\n\n\u003cp\u003ePublished preclinical studies have explored kinetin-related compounds and their interactions with PINK1-associated pathways. These investigations contribute to the scientific rationale behind CNS Curative's interest in kinetin.\u003c\/p\u003e\n\n\u003cp\u003eHowever, the biological activity observed in laboratory models cannot automatically be attributed to the finished NeuroClimax Gold (Simple) product.\u003c\/p\u003e\n\n\u003ch3\u003eNeuronal Function and Research Context\u003c\/h3\u003e\n\n\u003cp\u003eHealthy neuronal function involves several interconnected biological processes, including:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003eMitochondrial energy metabolism.\u003c\/li\u003e\n\u003cli\u003eCellular responses to oxidative stress.\u003c\/li\u003e\n\u003cli\u003eNeuronal signaling and cellular maintenance.\u003c\/li\u003e\n\u003cli\u003eSynaptic plasticity.\u003c\/li\u003e\n\u003cli\u003eNeurotrophic signaling pathways.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eBrain-derived neurotrophic factor (BDNF), for example, is a protein involved in neuronal development, survival, and synaptic plasticity.\u003c\/p\u003e\n\n\u003cp\u003eScientific investigations have examined relationships between mitochondrial function, oxidative stress, BDNF-related signaling, and neuronal biology.\u003c\/p\u003e\n\n\u003cp\u003eThese research areas provide background for the formulation's development. They should not be interpreted as demonstrated effects of NeuroClimax Gold (Simple) in humans.\u003c\/p\u003e\n\n\u003ch2\u003eNeuroClimax Gold™ (Simple) vs. Gold™ (Max)\u003c\/h2\u003e\n\n\u003cp\u003eCNS Curative offers two Gold formulations with different active-ingredient compositions.\u003c\/p\u003e\n\n\u003ch3\u003eNeuroClimax Gold™ (Simple)\u003c\/h3\u003e\n\n\u003cp\u003e\u003cstrong\u003eOne active ingredient:\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003eKinetin — investigated in preclinical research involving PINK1-related mitochondrial signaling.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eGold (Simple) provides a single-active-ingredient composition.\u003c\/p\u003e\n\n\u003ch3\u003eNeuroClimax Gold™ (Max)\u003c\/h3\u003e\n\n\u003cp\u003e\u003cstrong\u003eThree active ingredients:\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eKinetin:\u003c\/strong\u003e Investigated in research involving mitochondrial biology and PINK1-related signaling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNoopept:\u003c\/strong\u003e Studied in experimental research involving neuronal signaling, learning, and memory-related processes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCentrophenoxine:\u003c\/strong\u003e Investigated in research involving cholinergic function and cognitive processes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eGold (Max) combines multiple compounds with different research backgrounds, whereas Gold (Simple) contains only kinetin as its active ingredient.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eWhich formulation should you explore?\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cp\u003eIf your priority is understanding a single-active-ingredient composition, review Gold (Simple). If you want to examine a broader ingredient combination, explore Gold (Max).\u003c\/p\u003e\n\n\u003cp\u003eThis comparison describes formulation differences, not proven differences in effectiveness or safety.\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"\/products\/brain-health-support-against-brain-fog-and-brain-fatigue-with-neuroclimx-md\"\u003e\u003cstrong\u003eExplore NeuroClimax Gold™ (Max)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\n\u003ch2\u003eUnderstanding the Intranasal Formulation\u003c\/h2\u003e\n\n\u003cp\u003eNeuroClimax Gold (Simple) uses an intranasal administration format rather than conventional oral delivery.\u003c\/p\u003e\n\n\u003cp\u003eIntranasal delivery is an established area of pharmaceutical research because the nasal cavity provides an alternative route for administering certain compounds.\u003c\/p\u003e\n\n\u003cp\u003eHowever, the effectiveness, absorption, distribution, and safety of a particular intranasal formulation depend on its complete composition and supporting testing.\u003c\/p\u003e\n\n\u003cp\u003eThe use of an intranasal delivery system alone does not demonstrate superior absorption, improved brain delivery, or clinical effectiveness.\u003c\/p\u003e\n\n\u003ch3\u003eAdditional Formulation Components\u003c\/h3\u003e\n\n\u003cp\u003eAccording to the original CNS Curative product information, inactive formulation components may include:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003eSterile phosphate-buffered saline.\u003c\/li\u003e\n\u003cli\u003eCyclodextrins.\u003c\/li\u003e\n\u003cli\u003ePreservative agents.\u003c\/li\u003e\n\u003cli\u003eSolubilizing agents.\u003c\/li\u003e\n\u003cli\u003eSoothing or formulation-stabilizing excipients.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cstrong\u003ePlease note:\u003c\/strong\u003e This is a description of possible formulation components, not a verified complete ingredient declaration. Customers should consult the current product label or contact CNS Curative Technologies for the exact composition.\u003c\/p\u003e\n\n\u003ch2\u003eManufacturing and Product Information\u003c\/h2\u003e\n\n\u003cp\u003eNeuroClimax™ products are developed and manufactured by \u003cstrong\u003eCNS Curative Technologies LLC\u003c\/strong\u003e.\u003c\/p\u003e\n\n\u003cp\u003eAccording to the company's published product information, its manufacturing processes involve controlled sterile cleanroom conditions.\u003c\/p\u003e\n\n\u003cp\u003eCustomers seeking additional information about product specifications, manufacturing documentation, quality testing, storage requirements, or formulation ingredients can contact the company directly.\u003c\/p\u003e\n\n\u003cp\u003eManufacturing statements should be considered alongside the supporting documentation for the relevant product and production batch.\u003c\/p\u003e\n\n\u003ch2\u003eScientific Research and References\u003c\/h2\u003e\n\n\u003cp\u003eThe NeuroClimax scientific background draws on published investigations involving neuronal signaling, mitochondrial function, oxidative stress, and selected nootropic compounds.\u003c\/p\u003e\n\n\u003cp\u003eThe following references are retained from CNS Curative's existing product information:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003eCosta, A., et al. \u003cem\u003eFrontiers in Behavioral Neuroscience.\u003c\/em\u003e 2015;9:253.\u003c\/li\u003e\n\u003cli\u003eDagda, R.K., \u0026amp; Das Banerjee, T. \u003cem\u003eReviews in the Neurosciences.\u003c\/em\u003e 2015;26(3):359–370.\u003c\/li\u003e\n\u003cli\u003eHertz, N.T., et al. \u003cem\u003eCell.\u003c\/em\u003e 2013;154(4):737–747.\u003c\/li\u003e\n\u003cli\u003eSoman, S.K., et al. \u003cem\u003eJournal of Neuroscience Research.\u003c\/em\u003e 2021;99(9):2134–2155.\u003c\/li\u003e\n\u003cli\u003eOstrovskaya, R.U., et al. \u003cem\u003eBulletin of Experimental Biology and Medicine.\u003c\/em\u003e 2008;146(3):334–337.\u003c\/li\u003e\n\u003cli\u003eMarcer, D., \u0026amp; Hopkins, S.M. \u003cem\u003eAge and Ageing.\u003c\/em\u003e 1977;6(2):123–131.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThese references concern scientific research involving biological pathways and individual compounds. They do not, by themselves, establish the clinical safety or effectiveness of the finished NeuroClimax Gold (Simple) formulation.\u003c\/p\u003e\n\n\u003cp\u003eFor additional information about the company's research activities, visit \u003ca href=\"https:\/\/www.cnscurative.com\/\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eCNS Curative Technologies\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eIntellectual Property and Product Development\u003c\/h2\u003e\n\n\u003cp\u003eCNS Curative Technologies identifies the following provisional patent application in its published product documentation:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eU.S. Provisional Patent Application:\u003c\/strong\u003e 63\/897,520.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplication title:\u003c\/strong\u003e Treatment of Cognitive Decline and Fatigue with Intranasal Nootropic Formulations.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFirst named inventor:\u003c\/strong\u003e Raul Y. Dagda.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplicant:\u003c\/strong\u003e CNS Curative Technologies LLC.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReference:\u003c\/strong\u003e FHW081752.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThis information describes the company's reported intellectual property filing and does not represent a statement that a patent has been granted or that the product has received regulatory approval.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eNeuroClimax™\u003c\/strong\u003e is identified by CNS Curative Technologies LLC as its trademark.\u003c\/p\u003e\n\n\u003ch2\u003eBefore Ordering NeuroClimax Gold™ (Simple)\u003c\/h2\u003e\n\n\u003cp\u003eReview the product's complete ingredient information, current labeling, directions, warnings, and purchase terms before making a decision.\u003c\/p\u003e\n\n\u003cp\u003eIf you have questions about the formulation, ingredient concentrations, product suitability, or supporting documentation, contact CNS Curative Technologies before ordering. Seek advice from an appropriately qualified healthcare professional regarding individual medical considerations.\u003c\/p\u003e\n\n\u003cp\u003eThe product's current availability, pricing, and purchasing options are displayed separately on this page.\u003c\/p\u003e\n\n\u003cp\u003eFor ordering and customer-support information, visit:\u003c\/p\u003e\n\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/contact\"\u003eContact CNS Curative Technologies\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/policies\/shipping-policy\"\u003eShipping Information\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/policies\/refund-policy\"\u003eReturns and Refund Information\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eAbout CNS Curative Technologies\u003c\/h2\u003e\n\n\u003cp\u003e\u003cstrong\u003eCNS Curative Technologies LLC\u003c\/strong\u003e\u003cbr\u003e\n300 East 2nd Street\u003cbr\u003e\n15th Floor, Suite 1512\u003cbr\u003e\nReno, Nevada 89501\u003cbr\u003e\nUSA\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003ePhone:\u003c\/strong\u003e 775-376-0613\u003cbr\u003e\n\u003cstrong\u003eEmail:\u003c\/strong\u003e \u003ca href=\"mailto:contact@cnscurative.com\"\u003econtact@cnscurative.com\u003c\/a\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eCompany website:\u003c\/strong\u003e \u003ca href=\"https:\/\/www.cnscurative.com\/\" target=\"_blank\" rel=\"noopener noreferrer\"\u003ewww.cnscurative.com\u003c\/a\u003e\u003c\/p\u003e\n\n\u003ch2\u003eImportant Scientific and Safety Information\u003c\/h2\u003e\n\n\u003cp\u003e\u003cem\u003eThe scientific information presented here is based primarily on mechanistic, experimental, and preclinical research involving individual compounds and biological pathways.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eThese findings do not establish the clinical safety, effectiveness, appropriate dosing, or therapeutic benefits of the finished NeuroClimax Gold™ (Simple) formulation.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eProduct-specific regulatory status, safety documentation, labeling, and medical claims should be confirmed with CNS Curative Technologies and appropriately qualified regulatory professionals.\u003c\/em\u003e\u003c\/p\u003e","brand":"My Store","offers":[{"title":"1 month supply - Modified - Kinetin only","offer_id":47342034485397,"sku":"CNS 004","price":72.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0671\/3167\/0677\/files\/NeuroClimax_Gold_three_bottles.jpg?v=1791945318"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0671\/3167\/0677\/collections\/NeuroClimax_Advanced_with_one_bottle_and_packaging.jpg?v=1793551372","url":"https:\/\/www.cnscurative.store\/collections\/neuroclimax-nootropic-nasal-sprays.oembed","provider":"CNS Curative Store","version":"1.0","type":"link"}